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1

Gene Therapy with the Sleeping Beauty Transposon System

Kebriaei, Partow, Izsvák, Zsuzsanna, Narayanavari, Suneel A., Singh, Harjeet, Ivics, Zoltán

Journal:

Trends in Genetics

Year:

2017

Language:

english

File:

PDF, 3.64 MB

english, 2017

2

Translating Sleeping Beauty transposition into cellular therapies: Victories and challenges

Zsuzsanna Izsvák, Perry B. Hackett, Laurence J.N. Cooper, Zoltán Ivics

Journal:

Year:

2010

Language:

english

File:

PDF, 368 KB

english, 2010

3

Transposon-mediated genome manipulation in vertebrates

Ivics, Zoltán, Li, Meng Amy, Mátés, Lajos, Boeke, Jef D, Nagy, Andras, Bradley, Allan, Izsvák, Zsuzsanna

Journal:

Year:

2009

Language:

english

File:

PDF, 664 KB

english, 2009

4

Nonviral Gene Delivery with the Sleeping Beauty Transposon System

Ivics, Zoltán, Izsvák, Zsuzsanna

Journal:

Human Gene Therapy

Year:

2011

Language:

english

File:

PDF, 328 KB

english, 2011

5

The Ancient mariner Sails Again: Transposition of the Human Hsmar1 Element by a Reconstructed Transposase and Activities of the SETMAR Protein on Transposon Ends

Miskey, C., Papp, B., Mates, L., Sinzelle, L., Keller, H., Izsvak, Z., Ivics, Z.

Journal:

Molecular and Cellular Biology

Year:

2007

Language:

english

File:

PDF, 519 KB

english, 2007

6

How to tame an endogenous retrovirus: HERVH and the evolution of human pluripotency

Römer, Christine, Singh, Manvendra, Hurst, Laurence D, Izsvák, Zsuzsanna

Journal:

Current Opinion in Virology

Year:

2017

Language:

english

File:

PDF, 1.49 MB

english, 2017

7

iPSC-derived neural progenitors carrying a MT-ATP6 mutation exhibit mitochondrial hyperpolarization and calcium-related defects

Bukowiecki, Raul, Lesimple, Pierre, Lorenz, Carmen, Leong, Megan, Singh, Manvendra, Auré, Karine, Semtner, Marcus, L' Hermitte-Stead, Caroline, Wiesner, Burkhard, Izsvák, Zsuzsanna, Mielke, Thorsten,

Journal:

Year:

2015

Language:

english

File:

PDF, 70 KB

english, 2015

8

Efficient non-viral T cell engineering by Sleeping Beauty minicircles diminishing DNA toxicity and miRNAs silencing the endogenous TCR

Clauß, Julian, Obenaus, Matthias, Miskey, Csaba, Ivics, Zoltán, Izsvák, Zsuzsanna, Uckert, Wolfgang, Bunse, Mario

Journal:

Human Gene Therapy

Year:

2018

Language:

english

File:

PDF, 2.61 MB

english, 2018

9

A simple approach for multi-targeted shRNA-mediated inducible knockdowns using Sleeping Beauty vectors

Fink, Severin, Zugelder, Laurens, Roth, Bernhard, Brandt, Evelyn, Meloche, Sylvain, Izsvák, Zsuzsanna, Bargou, Ralf C., Stühmer, Thorsten, Kues, Wilfried A.

Journal:

Year:

2018

Language:

english

File:

PDF, 2.64 MB

english, 2018

10

Correction: Suicidal Autointegration of Sleeping Beauty and piggyBac Transposons in Eukaryotic Cells

Wang, Yongming, Wang, Jichang, Devaraj, Anatharam, Singh, Manvendra, Jimenez Orgaz, Ana, Chen, Jia-Xuan, Selbach, Matthias, Ivics, Zoltán, Izsvák, Zsuzsanna

Journal:

Year:

2019

Language:

english

File:

PDF, 234 KB

english, 2019

11

Translating Sleeping Beauty transposition into cellular therapies: Victories and challenges

Zsuzsanna Izsvák, Perry B. Hackett, Laurence J. N. Cooper, Zoltán Ivics

Journal:

Year:

2011

Language:

english

File:

PDF, 416 KB

english, 2011

12

The expanding universe of transposon technologies for gene and cell engineering

Zoltán Ivics, Zsuzsanna Izsvák

Journal:

Year:

2010

Language:

english

File:

PDF, 1.39 MB

english, 2010

13

Reliable transgene-independent method for determiningSleeping Beautytransposon copy numbers

Orsolya Kolacsek, Virág Krízsik, Anita Schamberger, Zsuzsa Erdei, Ágota Apáti, György Várady, Lajos Mátés, Zsuzsanna Izsvák, Zoltán Ivics, Balázs Sarkadi, Tamás I Orbán

Journal:

Year:

2011

Language:

english

File:

PDF, 887 KB

english, 2011

14

Characterization of aTc1-like transposable element in zebrafish (Danio rerio)

Zsuzsanna Izsvák, Zoltán Ivics, Perry B. Hackett

Journal:

Molecular Genetics and Genomics

Year:

1995

Language:

english

File:

PDF, 1.50 MB

english, 1995

15

DNA transposons in vertebrate functional genomics

C. Miskey, Z. Izsvák, K. Kawakami, Z. Ivics

Journal:

Cellular and Molecular Life Sciences

Year:

2005

Language:

english

File:

PDF, 281 KB

english, 2005

16

Molecular domestication of transposable elements: From detrimental parasites to useful host genes

L. Sinzelle, Z. Izsvák, Z. Ivics

Journal:

Cellular and Molecular Life Sciences

Year:

2009

Language:

english

File:

PDF, 2.21 MB

english, 2009

17

Targeted gene insertion for molecular medicine

Katrin Voigt, Zsuzsanna Izsvák, Zoltán Ivics

Journal:

Journal of Molecular Medicine

Year:

2008

Language:

english

File:

PDF, 407 KB

english, 2008

18

Hungary's 'reforms' are threatening basic science

Izsvák, Zsuzsanna, Ivics, Zoltán, Mátés, Lajos

Journal:

Year:

2006

Language:

english

File:

PDF, 92 KB

english, 2006

19

10.1038/75568

Kay, Mark A., Yant, Stephen R., Meuse, Leonard, Chiu, Winnie, Ivics, Zoltan, Izsvak, Zsuzsanna

Journal:

Nature Genetics

Year:

2000

Language:

english

File:

PDF, 670 KB

english, 2000

20

The hyperactive Sleeping Beauty transposase SB100X improves the genetic modification of T cells to express a chimeric antigen receptor

Jin, Z, Maiti, S, Huls, H, Singh, H, Olivares, S, Mátés, L, Izsvák, Z, Ivics, Z, Lee, D A, Champlin, R E

Journal:

Year:

2011

Language:

english

File:

PDF, 602 KB

english, 2011

21

Generating knockout rats by transposon mutagenesis in spermatogonial stem cells

Izsvák, Zsuzsanna, Fröhlich, Janine, Grabundzija, Ivana, Shirley, James R, Powell, Heather M, Chapman, Karen M, Ivics, Zoltán, Hamra, F Kent

Journal:

Year:

2010

Language:

english

File:

PDF, 491 KB

english, 2010

22

Sleeping Beauty hits them all: transposon-mediated saturation mutagenesis in the mouse germline

Izsvák, Zsuzsanna, Ivics, Zoltán

Journal:

Year:

2005

Language:

english

File:

PDF, 228 KB

english, 2005

23

Gateway-compatible transposon vector to genetically modify human embryonic kidney and adipose-derived stromal cells.

Dr. Spyros Petrakis, Tamas Raskó, Lajos Mátés, Zoltan Ivics, Zsuzsanna Izsvák, Kokkona Kouzi-Koliakou, George Koliakos

Journal:

Biotechnology Journal

Year:

2012

Language:

english

File:

PDF, 405 KB

english, 2012

24

Short Inverted-Repeat Transposable Elements in Teleost Fish and Implications for a Mechanism of Their Amplification

Izsvák, Zsuzsanna, Ivics, Zoltán, Shimoda, Nobuyoshi, Mohn, Deanna, Okamoto, Hitoshi, Hackett, Perry B.

Journal:

Journal of Molecular Evolution

Year:

1999

Language:

english

File:

PDF, 1.46 MB

english, 1999

25

Repetitive elements and genome instability

Zoltán Ivics, Zsuzsanna Izsvák

Journal:

Seminars in Cancer Biology

Year:

2010

Language:

english

File:

PDF, 166 KB

english, 2010

26

A whole lotta jumpin' goin' on: new transposon tools for vertebrate functional genomics

Zoltán Ivics, Zsuzsanna Izsvák

Journal:

Trends in Genetics

Year:

2005

Language:

english

File:

PDF, 91 KB

english, 2005

27

Resident aliens: the Tc1/mariner superfamily of transposable elements

Ronald H.A Plasterk, Zsuzsanna Izsvák, Zoltán Ivics

Journal:

Trends in Genetics

Year:

1999

Language:

english

File:

PDF, 239 KB

english, 1999

28

Sleeping Beauty, a wide host-range transposon vector for genetic transformation in vertebrates

Zsuzsanna Izsvák, Zoltán Ivics, Ronald H Plasterk

Journal:

Journal of Molecular Biology

Year:

2000

Language:

english

File:

PDF, 282 KB

english, 2000

29

Efficient stable gene transfer into human cells by the Sleeping Beauty transposon vectors

Zsuzsanna Izsvák, Marinee K.L. Chuah, Thierry VandenDriessche, Zoltán Ivics

Journal:

Year:

2009

Language:

english

File:

PDF, 537 KB

english, 2009

30

Sleeping Beauty transposon mutagenesis of the rat genome in spermatogonial stem cells

Zoltán Ivics, Zsuzsanna Izsvák, Karen M. Chapman, F. Kent Hamra

Journal:

Year:

2011

Language:

english

File:

PDF, 1002 KB

english, 2011

31

Common Physical Properties of DNA Affecting Target Site Selection of Sleeping Beauty and other Tc1/mariner Transposable Elements

Thomas J. Vigdal, Christopher D. Kaufman, Zsuzsanna Izsvák, Daniel F. Voytas, Zoltán Ivics

Journal:

Journal of Molecular Biology

Year:

2002

Language:

english

File:

PDF, 779 KB

english, 2002

32

Molecular Reconstruction of Sleeping Beauty, a Tc1-like Transposon from Fish, and Its Transposition in Human Cells

Zoltán Ivics, Perry B Hackett, Ronald H Plasterk, Zsuzsanna Izsvák

Journal:

Year:

1997

Language:

english

File:

PDF, 344 KB

english, 1997

33

Healing the Wounds Inflicted by Sleeping Beauty Transposition by Double-Strand Break Repair in Mammalian Somatic Cells

Zsuzsanna Izsvák, Eva E Stüwe, Dora Fiedler, Andrea Katzer, Penny A Jeggo, Zoltán Ivics

Journal:

Year:

2004

Language:

english

File:

PDF, 594 KB

english, 2004

34

Cloning and characterization of the genes of the CeqI restriction—modification system

Zsuzsa Izsvák, Zsolt Jobbágy, Imre Takács, Ernő Duda

Journal:

The International Journal of Biochemistry & Cell Biology

Year:

1997

Language:

english

File:

PDF, 552 KB

english, 1997

35

Germline transgenesis of the chordate Ciona intestinalis with hyperactive variants of sleeping beauty transposable element

Hozumi, Akiko, Mita, Kaoru, Miskey, Csaba, Mates, Lajos, Izsvak, Zsuzsanna, Ivics, Zoltan, Satake, Honoo, Sasakura, Yasunori

Journal:

Developmental Dynamics

Year:

2013

Language:

english

File:

PDF, 1.48 MB

english, 2013

36

The Sleeping Beauty transposon system for clinical applications

Swierczek, Marta, Izsvák, Zsuzsanna, Ivics, Zoltán

Journal:

Expert Opinion on Biological Therapy

Year:

2012

Language:

english

File:

PDF, 402 KB

english, 2012

37

Sleeping Beauty Transposon-Mediated Transfection of Retinal and Iris Pigment Epithelial Cells

Johnen, Sandra, Izsvák, Zsuzsanna, Stöcker, Michael, Harmening, Nina, Salz, Anna Katharina, Walter, Peter, Thumann, Gabriele

Journal:

Investigative Ophthalmology & Visual Science

Year:

2012

Language:

english

File:

PDF, 737 KB

english, 2012

38

Retargeting Sleeping Beauty Transposon Insertions by Engineered Zinc Finger DNA-binding Domains

Voigt, Katrin, Gogol-Döring, Andreas, Miskey, Csaba, Chen, Wei, Cathomen, Toni, Izsvák, Zsuzsanna, Ivics, Zoltán

Journal:

Molecular Therapy

Year:

2012

Language:

english

File:

PDF, 850 KB

english, 2012

39

Sleeping Beauty transposon mutagenesis in rat spermatogonial stem cells

Ivics, Zoltán, Izsvák, Zsuzsanna, Medrano, Gerardo, Chapman, Karen M, Hamra, F Kent

Journal:

Bioentrepreneur

Year:

2011

Language:

english

File:

PDF, 1.35 MB

english, 2011

40

Sleeping Beauty Transposition: Biology and Applications for Molecular Therapy

Journal:

Molecular Therapy

Year:

2004

Language:

english

File:

PDF, 528 KB

english, 2004

41

Technology transfer from worms and flies to vertebrates: transposition-based genome manipulations and their future perspectives

Lajos Mátés, Zsuzsanna Izsvák, Zoltán Ivics

Journal:

Year:

2007

Language:

english

File:

PDF, 2.41 MB

english, 2007

42

Regulation of DNA transposition by CpG methylation and chromatin structure in human cells

Tobias Jursch, Csaba Miskey, Zsuzsanna Izsvák, Zoltán Ivics

Journal:

Year:

2013

Language:

english

File:

PDF, 974 KB

english, 2013

43

Cell division promotes efficient retrotransposition in a stable L1 reporter cell line

Yi Xie, Lajos Mates, Zoltán Ivics, Zsuzsanna Izsvák, Sandra L Martin…

Journal:

Year:

2013

Language:

english

File:

PDF, 458 KB

english, 2013

44

Human endogenous retrovirus K (HML-2) RNA and protein expression is a marker for human embryonic and induced pluripotent stem cells

Fuchs, Nina V, Loewer, Sabine, Daley, George Q, Izsvák, Zsuzsanna, Löwer, Johannes, Löwer, Roswitha

Journal:

Year:

2013

Language:

english

File:

PDF, 513 KB

english, 2013

45

Germline transgenesis in pigs by cytoplasmic microinjection of Sleeping Beauty transposons

Ivics, Zoltán, Garrels, Wiebke, Mátés, Lajos, Yau, Tien Yin, Bashir, Sanum, Zidek, Vaclav, Landa, Vladimír, Geurts, Aron, Pravenec, Michal, Rülicke, Thomas, Kues, Wilfried A, Izsvák, Zsuzsanna

Journal:

Nature Protocols

Year:

2014

Language:

english

File:

PDF, 1.86 MB

english, 2014

46

Targeted Sleeping Beauty Transposition in Human Cells

Ivics, Zoltán, Katzer, Andrea, Stüwe, Eva E, Fiedler, Dora, Knespel, Siegne, Izsvák, Zsuzsanna

Journal:

Molecular Therapy

Year:

2007

Language:

english

File:

PDF, 333 KB

english, 2007

47

DANA Elements: A Family of Composite, tRNA-Derived Short Interspersed DNA Elements Associated with Mutational Activities in Zebrafish (Danio rerio)

Zsuzsanna Izsvák, Zoltán Ivics, David Garcia-Estefania, Scott C. Fahrenkrug and Perry B. Hackett

Journal:

Proceedings of the National Academy of Sciences

Year:

1996

Language:

english

File:

PDF, 1.05 MB

english, 1996

48

Identification of Functional Domains and Evolution of Tc1-Like Transposable Elements

Zoltán Ivics, Zsuzsanna Izsvák, Adam Minter and Perry B. Hackett

Journal:

Proceedings of the National Academy of Sciences

Year:

1996

Language:

english

File:

PDF, 1.19 MB

english, 1996

49

Chromosomal Transposition of a Tc1/Mariner-Like Element in Mouse Embryonic Stem Cells

Guangbin Luo, Zoltan Ivics, Zsuzsanna Izsvak and Allan Bradley

Journal:

Proceedings of the National Academy of Sciences

Year:

1998

Language:

english

File:

PDF, 1.58 MB

english, 1998

50

Repetitive elements and their genetic applications in zebrafish

Izsvák, Zsuzsanna, Ivics, Zoltan, Hackett, Perry B

Journal:

Biochemistry and Cell Biology

Year:

1997

File:

PDF, 2.62 MB

1997